Combined Anthocleista vogelii and Alstonia boonei Stem Barks Extract Alleviates Hyperlipidaemia and Renal Malfunctions in Benign Prostatic Hyperplasia-Induced Rats

Benign prostatic hyperplasia (BPH) is a urological disease prevalent among the ageing male population, which impairs quality of life, including hyperlipidaemia and decline in renal functions. Combining Anthocleista vogelii Alstonia boonei stem bark extract has effectively managed BPH its associated complications. This study evaluated effects combined (CAASBE) on lipid profile functions rats induced benign with testosterone propionate injection. The comprised five treatment groups, groups 1 – 5 being normal control, standard BPH+200 mg/kg CAASBE, BPH+400 respectively. was 2 4 by subcutaneous administration injection (5 mg/kg) for 28 days, Finasteride CAASBE were administered orally. control exhibited significant (p < 0.05) increase total serum cholesterol, triacylglycerol (TAG), low-density lipoprotein cholesterol (LDL-C), urea, creatinine high-density (HDL-C) compared to control. Conversely, 200 400 significantly reversed altered TAG, LDL-C, HDL-C, urea levels comparable that These findings show alleviates malfunctions suggesting it could be effective managing complication.